The peptide-HLA class I tetramer is a valuable tool for epitope screening and for rapid and detailed characterization of epitope specific CD8+T cells. The tetramer binds to the CD8+ T cell TCR with high avidity and specificity allowing for detection of specific T cells of frequencies lower than 0.05%.

The custom peptide-HLA I complexes are available as PE and APC labelled tetramers, or as biotinylated monomers. Monomers can readily be tetramerised with the label of your choice.

Please note that, a non-refundable setup fee of €350 applies to each custom peptide MHC class I complex in addition to the price of the complex. If a peptide MHC class I combination is unproductive, we only charge the setup fee.

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